Alpha GPC is a naturalcholine compound found in the brain and in milk. It is also a parasympathomimeticacetylcholine precursor which may have potential for the treatment of Alzheimer's disease and dementia. Alpha-GPC is also used as a nootropic dietary supplement to enhance memory and cognition.
Unlike most acetylcholine donors, Alpha GPC readily crosses the blood-brain barrier and results in high concentrations of acetylcholine in the brain. This makes it a perfect supplement to the racetams which deplete choline levels and it has compounding and synergistic effects with them and other nootropics. Because of its activity on short-term memory Alpha GPC has been studied and confirmed to be a successful treatment for those suffering from Alzheimers.In healthy adults, it has been shown to increase short-term memory and cognition.
Functions:
1. Increases human Growth Hormone (hGH)
Increases in endogenous human Growth Hormone (hGH) secretion by the anterior pituitary in conjunction with Growth Hormone Releasing Hormone (GHRH); that is, both Alpha-GPC and GHRH act concertedly to stimulate the release of hGH, naturally;
2. Improved mental focus and stimulation of cognitive function
Stimulation of the enzymatic synthesis of phosphatidylcholine (PC) in nerves, muscle cells and all cell membranes, counteracting the age-related decrease in phospholipid (PC) biosynthesis; thus, Alpha-GPC contributes directly to improved mental focus and stimulation of cognitive function;
3. More strength from work-outs and training programs
Acts as a precursor of acetylcholine (ACh); thus, Alpha-GPC activates cholinergic transmission which permits the development of more strength from work-outs and training programs, plus reducing levels of somatostatin in the hypothalamic-pituitary axis;
4. Improved lipotrophic functions in the liver
Elevations in blood and tissue levels of the essential nutrient, choline, which supports improved lipotrophic functions (methyl group transferases) in the liver. Research has shown that fatty liver, a condition associated with obesity, diabetes and heavy alcohol consumption, often leads to cirrhosis of the liver or liver failure. Studies conducted by Alan L. Buchman, M.D., associate professor of medicine at The Feinberg School of Medicine at Northwestern University, have shown that fatty liver can be prevented and possibly even eliminated with increased levels of choline. Alpha-GPC also acts synergistically with the body's store (and/or supplementation) of S-adenosyl-L-methionine (SAM or SAMe) and folic acid, vitamin B12 and vitamin B6 to facilitate methyl group transfers in the brain and liver;
5. Improved balanced and coordination
Produces improved balanced and coordination when combined with 'skill set' practice and training as a result of normalized nerve transmission in the brain, and in cardiac, skeletal and smooth muscles.
Product Name | L-a-glycerophosphorylcholine powder | |||
Molecular Formula | C8H20NO6P | CAS# | 28319-77-9 | |
Items | Specifications | Results | Analysis Method | |
Appearance | White powder, neutral odor, highly hygroscopic | Conforms | Visual | |
Identification | TLC:Standard solution and test solution same spot,RF | Conforms | TLC | |
Specific Optical | -2.4°~ -2.8° | -2.72° | ||
Heavy metals (as PB) | ≤10ppm | Conforms | AAS | |
Sulfate (SO4) | ≤0.02% | Conforms | Colorimetry | |
Chloride (Cl) | ≤0.02% | Conforms | Colorimetry | |
Phosphate Ion (P) | ≤5ppm | Conforms | Colorimetry | |
pH | 5.0~7.0 | 5.37 | ||
Related substance | Spot not bigger than standard solution spot | No spot | TLC | |
Residual solvent | ≤2.0% | Conforms | HS-GC | |
Water Content | ≤2% | 0.31% | KF | |
Assay (dried basis) | 98.0%--102.0% | 99.25% | Potentiometric titration | |
Result: Sample meets the Standard. |